Wybaczcie, trochę długie:
,,MHRA urgently seeks an Artificial Intelligence (AI) software tool to process the expected high volume of Covid-19 vaccine Adverse Drug Reaction (ADRs) and ensure that no details from the ADRs’ reaction text are missed.
The collection and analysis of Adverse Drug Reactions (ADRs) is a standard part of all drug development. Pharma companies employ hundreds of experts in “Patient Safety” teams and numerous IT systems and processes to handle it, and it is partly why drug development takes so long and costs so much. But if that is done by the drug companies then why does the UK regulator, MHRA, need its own ADR processing system?
The scrutiny of drugs does not stop when they get a license. Following the thalidomide tragedy in the 1960s, the WHO set-up adverse event [AE] vigilance systems in countries like the UK. Here it is called the Yellow Card scheme. You may never have heard of it, but there have been over 700,000 ADRs submitted since it was established. With the number of adverse events increasing dramatically each year, pharma companies and regulators are reaching the limits of what people can do accurately and efficiently. Heaping the nation’s largest ever mass vaccination campaign onto the regulator’s human based systems was not going to work. A problem for AI to solve? Perhaps Matt Hancock’s £250m National AI Lab, announced in August 2019, could help? Indeed MHRA were onto a similar idea as early as Oct 2018 when their board said:
MHRA has been encouraged to put forward bids to several government programmes for funding/ external resources to explore the utility of artificial intelligence (AI) to deliver enhanced vigilance capability.
Nearly two years later and how has the time and money been spent? Not all that productively it seems as on Sept 14th EU procurement rules had to be bypassed as a £1.5 million contract was urgently awarded to GenPact (UK) to process an estimated 25,000 to 50,000 ADR reports over a six- to 12-month period. Even then, the MHRA said the system would not be ready for the vaccine launch date.
Someone should tell Kate Bingham, chair of the UK’s vaccine task force, who said the use of AI was “just what the MHRA should be doing”, adding that the UK is “incredibly well set up to do this given we all have NHS records which are electronic and connected”. Err, no we don’t. Connecting all patient records in the NHS was the NPfIT programme, which cost £12.7 billion before being cancelled and described by a House of Commons enquiry as “one of the worst and most expensive contracting fiascos ever”.
Jak myślicie, że tylko w PL można coś widowiskowo i za ogromną kasę spierdzielić to się mylicie.
Ale zastanawiający jest fakt, adverse drug reaction jak ma wiele leków, spodziewana duża ilość więc program ma być doskonały by szczegółowo rejestrować wszystkie negatywne skutki po szczepionce.
Teraz rozumiecie chyba lepiej, że wraz z odpaleniem szczepionki zacznie się dopiero najwieksza chyba w ostatnich dziesięcioleciach faza testowa szczepionki na "adverse drug reaction" bo przecież jest jasne - stworzenie bezpiecznej szczepionki to lata badań które w tym wypadku pominięto. Co z ludźmi o osłabionej odporności i schorowanymi? Gdy podamy fragmenty wirusa by wytworzyć przeciwciała stawiamy organizm w podobnej sytuacji jak przy standardowym zarażeniu - układ odpornościowy jedzie na cały gwizdek by zneutralizować nieaktywne szczatki wirusa i w tym momencie jest łatwo o standardowe zarażenie nie tylko sars2+ ale innymi chorobami.
Stad tzw.fenomen szczepienia na grype po którym mały % ludzi przechodzi ją naprawdę ciężko. Ktoś miał grypę po szczepionce na grypę? Ja miałem z 10-12 lat temu, chyba najcięższą. Od tamtego czasu jeśli mam grypę to 3 dni i piwo z miodem oraz czosnek z vindaloo rozwiązuja problem bez żadnych proszków.
Brzmi jak szczury laboratoryjne? Ano nimi będziemy.
I never thought I’d live in a world where people are so afraid of dying that they stop living..